SKIN - Simple Abscess, Furuncle, Carbuncle, Folliculitis (Staphylococcus aureus, Streptococcus sp.)
Dicloxacillin (Dynapen^®) Generics available Pregnancy: B; Lactation: Unk Caps: 125 mg, 250 mg, 500 mg Oral Susp: 62.5 mg/5 mL	Children ≤ 40 kg: 25-50 mg/kg/day (max 2 g/day) in divided doses every 6 hours for 10-14 days. 62.5 mg/5 mL @ 25 mg/kg/day (double for 50 mg)		Food: Take 1 hour before or 2 hours after meals. Important side effects: Bad taste, GI upset, vomiting, diarrhea.
	10 kg (22 lb) = 1 tsp (5 mL) Q6H 15 kg (33 lb) = 1½ tsp (7.5 mL) Q6H 20 kg (44 lb) = 2 tsp (10 mL) Q6H 40 kg (88 lb) = Use adult dose. Children ≥40 kg and Adult: 250-500 mg PO four times daily for 10-14 days.
Cephalexin (Keflex^®) Generics available Pregnancy: B; Lactation: Unk Tabs: 250 mg, 500 mg, 1 g Caps: 250 mg, 500 mg Oral Susp: 125 mg/5 mL, 250 mg/5 mL -	Children: 25-50 mg/kg/day (max 4 g/day) in divided doses two to four times daily for 10-14 days. 125 mg/5 mL @ 25 mg/kg/day (double for 50 mg/kg) 10 kg (22 lb) = ½ tsp (2.5 mL) Q6H 15 kg (33 lb) = ¾ tsp Q6H 250 mg/5 mL @ 25 mg/kg/day (double for 50 mg/kg) 20 kg (44 lb) = ½ tsp (2.5 mL) Q6H 40 kg (88 lb) = 1 tsp (5 mL) Q6H >40 kg = Use adult dose. Adult: 500 mg PO two to four times daily for 10-14 days.		Food: Take 1 hour before or 2 hours after meals. May take with food if GI upset occurs. Important side effects: GI upset, diarrhea. Reduce dose if renal disease (CrCl <40 mL/min).
Amoxicillin/clavulanate (Augmentin^®) Pregnancy: B; Lactation: Unk	Children: 40-45 mg amoxicillin component/kg/day (max 1600 mg/day) in divided doses two or three times daily for 7-14 days.		Food: Take with food to reduce diarrhea. Important side effects: Diarrhea (common), nausea, rash.
Q12H Formulations: Tabs: 500 mg/125 mg, 875 mg/125 mg Chewable Tabs: 200 mg/28.5 mg, 400 mg/57 mg Oral Susp: 200 mg/28.5 mg/5 mL, 400 mg/57 mg/5 mL	Q12H using 200 mg/5 mL susp @ 45 mg/kg/day 9 kg (20 lb) = 1 tsp (5 mL) Q12H 13 kg (29 lb) = 1½ tsp (7.5 mL) Q12H 18 kg (40 lb) = 2 tsp (10 mL) Q12H Q12H using 400 mg/5 mL susp @ 45 mg/kg/day 18 kg (40 lb) = 1 tsp (5 mL) Q12H 27 kg (59 lb) = 1½ tsp (7.5 mL) Q12H 35 kg (77 lb) = 2 tsp (10 mL) Q12H >40 kg = Use adult dose (max 875 mg Q12H ) Adult: 500-875 mg twice daily for 7-14 days. Note: Q12H dosing may improve compliance compared to Q8H dosing.		Use with caution in hepatic disease. Reduce dose in renal disease (CrCl <30 mL/min).
Clindamycin A drug of choice for patients with penicillin or cephalosporin intolerance. (Cleocin^®) Generics available Pregnancy: B; Lactation: Unk Caps: 75 mg, 150 mg, 300 mg Oral Solution: 75 mg/5 mL 150 mg/10 mL	Children: Mild to Moderate: 10-15 mg/kg/day (max 1.8 g/day) PO in divided doses three or four times daily for 10-14 days. Children: Severe: 16-25 mg/kg/day (max 1.8 g/day) in divided doses three or four times daily for 10-14 days. 75 mg/5 mL @ 10 mg/kg/day divided 10 kg (22 lb) = ½ tsp (2.5 mL) Q8H 20 kg (44 lb) = 1 tsp (5 mL) Q8H 30 kg (66 lb) = 1½ tsp (7.5 mL) Q8H 40 kg (88 lb) = 2 tsp (10 mL) Q8H >40 kg = Use adult dose.		Food: May take with or without meals. Take with full glass of water to prevent esophagitis. Important side effects: Diarrhea (may be severe), nausea. May cause severe colitis. Encourage patient to report severe, persistent, or bloody diarrhea.
	Adult: Mild to Moderate: 150-300 mg PO three to four times daily for 10-14 days. Adult: Severe: 450 mg PO four times daily for 10-14 days.
Erythromycin estolate or base A drug of choice for patients with penicillin or cephalosporin intolerance (E-mycin^®, Ilosone ^®) Generics available Pregnancy: B; Lactation: Unsafe	Children: 20-40 mg/kg/day estolate (max 2 g/day) in two to four divided doses daily for 10-14 days. 125 mg/5 mL @ 20 mg/kg/day 4-6 kg (10-15 lb) = ½ tsp (2.5 mL) Q12H 7-11 kg (16-25 lb) = 1 tsp (5 mL) Q12H	Food: May take with or without meals. Take with food if causes GI upset. Important side effects: GI upset, hepatitis.
Estolate:	12-16 kg (26-35 lb) = 1½ tsp (7.5 mL)
Tabs: 500 mg	Q12H
Caps: 250 mg	250 mg/5 mL @ 20 mg/kg/day
Susp: 125 mg/5 mL and 250 mg/5 mL 250 mg/5 mL Q12H × 10 days -   Base: Tabs: 250 mg, 333 mg, 500 mg Caps: 250 mg 500 mg PO Q6H × 10 days -	17-25 kg = 1 tsp (5 mL) Q12H 26-37 kg = 1½ tsp (7.5 mL) Q12H >38 kg = 500 mg Q12H Adult: Erythromycin base or estolate 500 mg PO four times daily for 10-14 days.