GENITOURINARY - Bacterial Vaginosis (Anaerobes, Gardnerella vaginalis, Mycoplasma hominis, polymicrobial)
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Metronidazole* (Flagyl®) Generics available Pregnancy: B; Lactation: Unsafe Tabs: 250 mg, 500 mg |
Adult: 500 mg twice daily for 7 days or 2 g given as a one time dose. (2-g dosing may be less effective than the 7-day regimen.) |
Food: Administer on empty stomach unless GI upset occurs, then with food.
Important side effects: Dizziness, headache, confusion, seizures, nausea, metallic taste, insomnia, paresthesias. May cause Disulfiram-like reaction - avoid alcohol.
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Clindamycin Vaginal Cream* (Cleocin®) Pregnancy: B; Lactation: Unknown
Vaginal Cream 2%: 40 g
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Adolescent and Adult: Insert one applicator (5 g) intravaginally each night at bedtime for 7 days. |
Important side effects: May weaken latex condoms or diaphragms. Advise patient not to engage in vaginal intercourse while using this product.
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Metronidazole gel* (MetroGel®-Vaginal) Pregnancy: B; Lactation: Unk
Gel, vaginal 0.75%: 70 g
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Adult: Insert one applicator (5 g) intravaginally twice daily for 5 days. |
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Clindamycin* (Cleocin®) Generics available Pregnancy: B; Lactation: Unk
Caps: 150 mg - , 300 mg |
Adult: 300 mg twice daily for 7 days.
*May cause severe colitis. Encourage patient to report severe, persistent, or bloody diarrhea.
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Food: May administer without regard to food. Take with full glass of water to prevent esophagitis.
Important side effects: Diarrhea (may be severe), esophagitis.
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