GENITOURINARY - Bacterial Vaginosis, Pregnancy (Anaerobes, Gardnerella vaginalis, Mycoplasma hominis, polymicrobial)
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Metronidazole* (Flagyl®) Generics available Pregnancy: B; Lactation: Unsafe
Tabs: 250 mg, 500 mg |
Adult: 250 mg PO three times daily for 7 days or 2 g once. (2-g dosing may be less effective than the 7 day regimen). |
Food: Administer on empty stomach unless GI upset occurs, then with food.
Important side effects: Dizziness, headache, confusion, seizures, nausea, metallic taste, insomnia, paresthesias. May cause disulfiram-like reaction—avoid alcohol.
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Clindamycin* (Cleocin®) Generics available Pregnancy: B; Lactation: Unknown
Caps: 150 mg , 300 mg |
Adult: 300 mg PO twice daily for 7 days.
*May cause severe colitis. Encourage patient to report severe, persistent, or bloody diarrhea. |
Food: May administer without regard to food. Take with full glass of water to prevent esophagitis.
Important side effects: Diarrhea (may be severe), esophagitis.
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