Drug
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Typical Dosing |
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Cefadroxil Duricef® Generics available Pregnancy: B; Lactation: Use with caution
Caps: 500 mg Tabs: 1 g Powder for Oral Suspension: 250 mg/5 mL 500 mg/5 mL |
Children: 30 mg/kg/day (max 2000 mg/day) PO in divided doses once or twice daily (depends upon indication).
250 mg/5 mL @ 30 mg/kg/day 9 kg (20 lb) = 1/2 tsp (2.5 mL) Q12H or 1 tsp (5 mL) Q24H 18 kg (40 lb) = 1 tsp (5 mL) Q12H or 2 tsp (10 mL) Q24H 27 kg (60 lb) = 2 tsp (10 mL) Q12H or 4 tsp (20 mL) Q24H
Adult: 1,000-2000 mg/day PO in divided doses once or twice daily.
Food: May be taken without regard to food. May take with food to reduce GI upset.
Important side effects: Nausea, vomiting, rash, diarrhea, elevated LFTs.
Caution: Avoid use in patients with history of severe penicillin allergy. Use with caution in patients with history of seizures.
Reduce dose in renal disease: CrCl 10-25 mL/min increase dose interval to every 24 hours. CrCl <10 mL/min increase dose interval to every 36 hours. |