Drug
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Typical Dosing |
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Cefprozil Cefzil® Pregnancy: B; Lactation: Unk
Tabs: 250, 500mg
Powder for Oral Suspension: 125 mg/5 mL 250 mg/5 mL
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Children ≥6 months to 12 years: 7.5-15 mg/kg/day in divided doses 2 times daily (max 1,000 mg/day).
250 mg/5 mL @ 30 mg/kg/day 9.1 kg (20 lb) = 1/2 tsp (2.5 mL) Q12H 13.6 kg (30 lb) = 3/4 tsp Q12H 18.2 kg (40 lb) = 1 tsp (5 mL) Q12H 27 kg (60 lb) = 11/2 tsp (7.5 mL) Q12H 31 kg (70 lb) = Use adult dose.
≥13 years to Adult: 250 mg Q12H or 500 mg once or twice daily.
Food: May be taken without regard to food. May take with food to reduce GI upset.
Important side effects: Nausea, vomiting, rash, diarrhea, elevated LFTs.
Caution: Avoid use in patients with history of severe penicillin allergy. Use with caution in patients with history of seizures.
Reduce dose in renal disease: CrCl <30 mL/min administer 50% of usual dose at standard dosing interval. |