Drug

Typical Dosing

Ceftriaxone Rocephin^® Pregnancy: B; Lactation: Unk Powder for IM or IV injection: 250 mg, 500 mg, 1,000 mg

Children: 25-75 mg/kg/day IM or IV in one or two divided doses (max 2000 mg/day) Adult: Usual dose 250 mg-2 g IM or IV once daily. Maximum dose 2 g Q12H. Important side effects: Rash, diarrhea, elevated LFTs. Reduce dose in patients with combined liver disease and significant renal disease. Caution: Avoid use in patients with history of severe penicillin allergy. Use with caution in patients with history of seizures. Use with caution in patients with history of biliary disease.