Drug

 

 

Typical Dosing

 

 

Ciprofloxacin

Cipro®

Pregnancy: C; Lactation: Unsafe

 

Tabs: 250 mg

500 mg

750 mg

 

Oral Suspension:

250 mg/5 mL

500 mg/5 mL

 

≥18 years to Adult: 250-750 mg PO two times daily.

 

Food: Take on empty stomach 1 hour before or 2 hours after a meal. Take 2 hours before or 6 hours after sucralfate, antacids, aluminum, magnesium, calcium, zinc, iron, sucralfate, vitamins, or mineral supplements.

 

Important side effects: Photosensitivity, dizziness, headache, insomnia, rash (may be severe), seizures, superinfection, angina, atrial flutter, bronchospasm.

 

Drug Interactions: May be significant with ciprofloxacin, especially caffeine, phenytoin, cyclosporine, warfarin, theophylline.

 

Reduce dose in renal disease:

CrCl 30-50 mL/min 250-500 mg PO Q12H

CrCl 5-29 mL/min 250-500 mg PO Q18H