Drug	Typical Dosing

Doxycycline Vibramycin^® Generics available Pregnancy: D; Lactation: Unsafe Caps: 50 mg 100 mg Tabs: 100 mg Powder for Oral Suspension: 25 mg/5 mL Syrup: 50 mg/5 mL

Children: 2-4 mg/kg/day (max 200 mg/day) in two divided doses. Children ≥8 years and Adult: 50-100 mg twice daily. Use in children <8 years old is generally not advised because tetracyclines can retard skeletal development and stain dental enamel. Doxycycline may have a role in some children <8 years old in certain tick-borne diseases. The dental risk is less than other tetracyclines and is related to duration of use. Food: May take with food if GI upset occurs. Take 1 hour before or 2 hours after antacids, iron, milk, or other dairy products. Take with full glass of water to minimize esophagitis. Important side effects: Photosensitivity, use sunscreen. Esophagitis, take with full glass of water. May discolor fingernails. Rash, nausea, diarrhea, superinfection, hepatitis. Outdated tetracyclines are toxic and should not be used.