GASTROINTESTINAL - Diarrhea, Giardia (protozoal)
|
|||
Metronidazole (Flagyl®) Generics available Pregnancy: B; Lactation: Unsafe Tabs: 250 mg, 500 mg |
Children: 15 mg/kg/day (max 300 mg/day) in divided doses three times daily for 5-10 days. Adult: 250 mg three times daily for 7 days. |
Food: Administer on empty stomach unless GI upset occurs, then with food.
Important side effects: Dizziness, headache, confusion, seizures, nausea, metallic taste, insomnia, paresthesias. May cause Disulfiram-like reaction - avoid alcohol.
|
|
GASTROINTESTINAL - Diarrhea (Salmonella typhi)
|
|||
Ciprofloxacin (Cipro®) Pregnancy: C; Lactation: Unsafe
Tabs: 250 mg, 500 mg, 750 mg |
³ 18 and Adult: 500 mg PO twice daily for 5-7 days. |
Food: Take on empty stomach 1 hour before or 2 hours after a meal. May take with food if it causes GI upset, but avoid large amounts of dairy products. May take 2 hours before or 6 hours after sucralfate, antacids, aluminum, magnesium, calcium, zinc, iron, sucralfate, vitamins, or mineral supplements.
|
|
|
|
Important side effects: Photosensitivity, dizziness.
Reduce dose in renal disease (CrCl <50 /min).
|
|
Azithromycin (Zithromax®) Pregnancy: B; Lactation: Unk
Tabs: 250 mg
|
Adult: 1,000 mg PO once, then 500 mg PO once daily for 6 days. |
Food: Oral suspension should be taken 1 hour before or 2 hours after food. Tablets may be taken without regard to food.
Important side effects: Nausea, diarrhea, elevated LFTs.
|
|
Trimethoprim/Sulfamethoxazole (Bactrim®, Septra®) Generics available Pregnancy: C; Lactation: Unsafe
Single Strength (SS) Tabs: 80 mg/400 mg
Double Strength (DS) Tabs: 160 mg/800 mg –
Susp: 40 mg/200 mg/5 mL *Resistance may be increasing. |
Children: 6-12mg/kg/day (trimethoprim component, max 320 mg/day) in divided doses two time daily for 5-7 days.
40 mg/200 mg/5 mL @ 8 mg/kg/day 10 kg (22 lb) 5 mL Q12H 20 kg (44 lb) 10 mL or 1 SS Tablet Q12H 30 kg (66 lb) 15 mL Q12H 1½ SS Tablet Q12H 40 kg (88 lb) 20 mL or 2 SS Tab or 1 Septra DS Q12H
Adult: 1 DS tablet PO twice daily for 5-7 days.
|
Food: May take without regard to food. Encourage fluids.
Important side effects: Photosensitivity, rash.
Reduce dose in renal disease (CrCl <30 mL/min). |
|
|
|
||
GASTROINTESTINAL - Diarrhea, Staphylococcus aureus Antibiotic treatment not recommended
|
|||
|
|||
Metronidazole (Flagyl®) Pregnancy: B; Lactation: Unsafe
|
Children: 35-50 mg/kg/day (max 750 mg/dose) in divided doses three times daily for 5-10 days. |
Food: Administer on empty stomach unless GI upset occurs, then with food. |
|
Tabs: 250 mg, 375 mg, 500 mg Flagyl ER: 750 mg - |
Adult: 750 mg three times daily for 5-10 days. |
Important side effects: Dizziness, headache, confusion, seizures, nausea, metallic taste, insomnia, paresthesias. May cause Disulfiram-like reaction - avoid alcohol.
|
|
GASTROINTESTINAL - Diarrhea, Campylobacter jejuni
|
|||
Ciprofloxacin (Cipro®) Pregnancy: C; Lactation: Unsafe
Tabs: 250 mg, 500 mg, 750 mg - *Resistance is increasing. |
³ 18 and Adult: 500 mg PO twice daily for 3-5 days. |
Food: Take on empty stomach 1 hour before or 2 hours after a meal. May take with food if it causes GI upset, but avoid large amounts of dairy products. May take 2 hours before or 6 hours after sucralfate, antacids, aluminum, magnesium, calcium, zinc, iron, sucralfate, vitamins, or mineral supplements.
Important side effects: Photosensitivity, dizziness.
Reduce dose in renal disease (CrCl <50 mL/min).
|
|
Azithromycin (Zithromax®) Pregnancy: B; Lactation: Unk
Tabs: 250 mg |
Adult: 500 mg PO once daily for 3 days. |
Food: Oral suspension should be taken 1 hour before or 2 hours after food. Tablets may be taken without regard to food.
Important side effects: Nausea, diarrhea, elevated LFTs.
|
|
Erythromycin Base (E-Mycin®, Ery-Tab®) Pregnancy: B; Lactation: Safe
Estolate: Tabs: 500 mg Caps: 250 mg Susp: 125 mg/5 mL, 250 mg/5 mL Oral Drops: 100 mg/mL
Base: Tabs: 250 mg, 333 mg, 500 mg Caps: 250 mg |
Children: 30-50 mg/kg/day (max 2000 mg/day) in divided doses four times 5-7 days.
200 mg/tsp @ 50 mg/kg/day 4-6 kg (10-15 lb) = ¼ tsp Q6H 7-11 kg (16-25 lb) = × tsp (2.5 mL) Q6H 11-22 kg (26-50 lb) = 1 tsp (5 mL) Q6H 23-45 kg (51-100 lb) = 1½ tsp (7.5 mL) Q6H >100 lb = Use adult dose.
Children <6 years: 125 mg PO three times daily 10-14 days . Adult: 250-500 mg PO four times daily for 5-7 days.
|
Food: Take 1 hour before or 2 hours after meals. If GI upset occurs may take with food.
Important side effects: Diarrhea, nausea, vomiting, headache, abdominal pain, dizziness, elevated LFTs, superinfection, rash, hearing loss, cardiac arrthythmias. |
|