BRONCHOPULMONARY - Influenza (Haemophilus influenzae types A, B)       

The data on effectiveness is limited. Most only shorten s/s by 8 hours.     

                                                                                                                             

 

Amantadine

(Influenza A only) (Symmetrel®)

Pregnancy: C; Lactation: Unk

Caps: 100 mg

Tabs: 100 mg

Syrup: 50 mg/5 mL 5 days

 

Children (1-9 years): 5 mg/kg/day twice daily (max 150 mg/day) 5 days

 

Children (10-12 years): 5 mg/kg/day twice daily (max 200 mg/day)  5 days 50 mg/mL @ 5 mg/kg/day

 

5 kg   (11 lb) = 1/4 tsp Q12H

10 kg (22 lb) = 1/2 tsp (2.5 mL) Q12H

15 kg (33 lb) = 3/4 tsp Q12H

20 kg (44 lb) = 1 tsp (5 mL) Q12H

 

Adult: 13-64 years: 100 mg Q12H ´ 5 days

 

Adult >65: 100 mg once daily ´ 5 days

 

 

Food: With or without meals. Avoid excessive alcohol.

 

Important side effects: Anxiety, nervousness, nausea.

 

Oseltamivir

(Influenza A and B) (Tamiflu®)

Pregnancy: C; Lactation: Unk

 

Caps: 75 mg

Powder: 12 mg/mL

 

Children 1-12 years: ´ 5 days.

12 mg/mL Suspension

<15 kg (33 lb) = 2.5 mL Q12H

<15-23 kg (34-50 lb) = 3.8 mL Q12H

>23-40 kg (50-88 lb) = 5 mL Q12H

>40 kg (88 lb) = 6.2 mL Q12H

 

Adult: 75 mg Q12H ´ 5 days.

 

 

Food: With or without meals.

 

Important side effects: Nausea, vomiting that can be reduced with food.

 

Rimantadine

(Influenza A only) (Flumadine®)

Pregnancy: C; Lactation: Unk

 

Tabs: 100 mg

Syrup: 50 mg/5 mL   

 

Children: Rimantadine is only approved for prophylaxis in young children. However, experts consider it appropriate for treatment of influenza in children of all ages.

 

 

Food: With or without meals.

 

Mportant side effects: Nausea, vomiting, nervousness, anxiety. Use with caution on patients with history of seizure disorder, renal or hepatic disease.

Children >13 or adults: 100 mg Q12H ´ 7 days.

 

Elderly: Reduce dose to 100 mg Q24H

 

 

Zanamivir

(Influenza A and B) (Relenza®)

Pregnancy: C; Lactation: Unk

 

Rotadisk: 5-mg blisters of powder for inhalation. 5 days -    

 

 

Adults and Children >7 years:

2 inhalations Q12H ´ 5 days.

 

Food: N/A

 

Important side effects: Caution in patients with history of bronchospasm.