PHARYNX / NECK - Gonococcal Pharyngitis (Neisseria gonorrhoeae)
Ceftriaxone (IM) (Rocephin^®) Pregnancy: B; Lactation: Unk Vials: 250 mg, 500 mg, 1,000 mg Vials with 2.1 mL Lidocaine for IM injection: 500 mg, 1,000 mg	Children and Adult: 125 mg IM × 1 dose. Children ≥45 kg and adults treat with concomitant azithromycin or doxycycline for presumptive C. trachomatis.	Important side effects: Pain at injection site.
Azithromycin* (Zithromax^®) Pregnancy: B; Lactation: Unk Tabs: 250 mg    Powder for Oral Suspension: 1 g	Children ≥45 kg and Adult: 1 g PO × 1 dose. Use in conjunction with ceftriaxone, ciprofloxacin, or ofloxacin.	Food: Oral suspension should be taken 1 hour before or 2 hours after food. Tablets may be taken without regard to food. Important side effects: Nausea, diarrhea, elevated LFTs.
Ciprofloxacin* (Cipro^®) Pregnancy: C; Lactation: Unsafe Tabs: 250 mg, 500 mg	≥18 years: 500 mg PO × 1 dose. Treat concomitantly with azithromycin or doxycycline for presumptive C. trachomatis.	Food: May take with food if it causes GI upset, but avoid large amounts of dairy products. May take 2 hours before or 6 hours after sucralfate, antacids, aluminum, magnesium, calcium, zinc, iron, vitamins, or mineral supplements. Important side effects: Photosensitivity and dizziness.
Doxycycline* (Vibramycin^®) Generics available Pregnancy: D; Lactation: Unsafe Caps: 50 mg, 100 mg Tabs: 50 mg, 100 mg	Children ≥8 years and Adult: 100 mg PO twice daily for 7 days. Use in conjunction with ceftriaxone, ciprofloxacin, or ofloxacin.	Food: May take with food if GI upset occurs. Take 1 hour before or 2 hours after antacids, iron, milk, or other dairy products. Take with full glass of water to prevent esophagitis. Important side effects: Photosensitivity (use sunscreen), esophagitis. May discolor fingernails.
Ofloxacin* (Floxin^®) Pregnancy: C; Lactation: Unk Tabs: 200 mg, 300 mg, 400 mg	≥ 18 years: 400 mg PO × 1 dose. Treat concomitantly with azithromycin or doxycycline for presumptive C. trachomatis.	Food: May take without regard to food. Do not take within 2 hours of sucralfate, antacids, aluminum, magnesium, calcium, zinc, iron, vitamins, or mineral supplements.
		Important side effects: Nausea, photosensitivity, dizziness.
PHARYNX / NECK - Gonococcal Pharyngitis in Pregnancy (Neisseria gonorrhoeae)
Ceftriaxone (IM) (Rocephin^®) Pregnancy: B; Lactation: Unk	Adolescents and Adult: 125 mg IM × 1 dose. Treat concomitantly with erythromycin or amoxicillin for presumptive C. trachomatis.	Important side effect: Pain at injection site.
Amoxicillin (Amoxil^®) Generics available Pregnancy: B; Lactation: Safe Caps: 250 mg, 500 mg	Adolescents and Adult: 500 mg PO three times daily for 7 days. Use in conjunction with ceftriaxone, cefixime, or spectinomycin.	Food: May take with or without meals. Important side effects: Diarrhea and nausea. May cause nonallergic maculopapular rash.
Cefixime (Suprax^®) May be less effective than ceftriaxone in oropharyngeal infection, but is a useful oral alternative. Pregnancy: B; Lactation: Unk Tabs: 200 mg, 400 mg	Adolescents and Adult: 400 mg PO × 1 dose. Treat concomitantly with erythromycin or amoxicillin for presumptive C. trachomatis.	Food: May be taken without regard to food. Food may reduce GI upset. Important side effects: Rash, nausea, diarrhea.
Erythromycin Base (E-Mycin^®, Ery-Tab^®) Generics available Pregnancy: B; Lactation: Safe Tabs: 250 mg, 333 mg, 500 mg   Caps: 250 mg	Adolescents and Adult: 500 mg PO four times daily for 7 days or if GI intolerance, 250 mg PO four times daily for 14 days. Use in conjunction with ceftriaxone, cefixime, or spectinomycin.	Food: May take with or without meals. Take with food if causes GI upset. Important side effects: GI upset, hepatitis.