PHARYNX / NECK - Tonsillitis/Pharyngitis (Haemophilus influenzae)

 

 

Azithromycin

(Zithromax®)

Pregnancy: B; Lactation: Unk

 

Tabs: 250 mg and Z-Pak

 

Oral Susp: 100 mg/5 mL, 200 mg/5 mL

 

Children ≥6 months:

10 mg/kg/day (max 500 mg) PO daily × 1 day, then 5 mg/kg/day (max 250 mg)

PO daily 4 days

 

100 mg/5 mL

10 kg (22 lb) = 1 tsp (5 mL) × 1 day, then ½ tsp (2.5 mL) daily for days 2-5.

 

200 mg/5 mL

20 kg (44 lb) = 1 tsp (5 mL) × 1 day, then ½ tsp (2.5 mL) daily for days 2-5. 30 kg (66 lb) = 1.5 tsp × 1 day, then ¾ tsp daily for days 2-5.

 

Adult: Dispense one Z-Pak.

 

 

Food: Oral suspension should be taken 1 hour before or 2 hours after food.

Tablets may be taken without regard to food.

 

Important side effects: Nausea, diarrhea, elevated LFTs.

 

 

 

Cefuroxime axetil

(Ceftin®)

Pregnancy: B; Lactation: Unsafe

 

Tabs: 125 mg, 250 mg, 500 mg

 

Oral Susp: 125 mg/5 mL, 250 mg/5 mL

 

 

Children >3 months to 12 years:

30 mg/kg/day (max 1,000 mg/day) in divided doses twice daily for 10 days.

 

125 mg/5 mL @ 30 mg/kg/day

8 kg (18 lb) = 1 tsp (5 mL) Q12H

12.5 kg (27 lb) = 1½ tsp (7.5 mL) Q12H

17 kg (37 lb) = 2 tsp (10 mL) Q12H

25 kg (55 lb) = 3 tsp (15 mL) Q12H

33 kg (73 lb) = Use adult dose.

 

Children ≥13 years or Adult: 250-500 mg PO twice daily for 10 days.

 

Food: Take suspension with food. Tablets may be taken without regard to food.

 

Important side effects: Nausea, vomiting, diarrhea.

Reduce dose in renal disease (CrCl <30 mL/min).

 

Trimethoprim/Sulfamethoxazole*

(Bactrim®, Septra®)

 

Children >2 months:

8-10 mg/kg/day TMP component (max 320 mg/day) in divided doses twice

daily for 10-14 days.

 

8-10 mg/kg/day @ 40 mg/200 mg/5 mL

10 kg (22 lb) = 1 tsp (5 mL) Q12H

 

20 kg (44 lb) = 2 tsp (10 mL) or

1 SS Tab Q12H

 

30 kg (66 lb) = 3 tsp (15 mL) or

1½ SS Tab Q12H

 

40 kg (88 lb) = 4 tsp (20 mL) or

2 SS Tabs or 1 DS Tab Q12H

 

Adult: 1 DS Tab PO twice daily for

10-14 days.

 

 

Food: May take without regard to food. Encourage fluids.

 

Important side effects: Photosensitivity, rash.

 

Reduce dose in renal disease (CrCl <30 mL/min).