PHARYNX / NECK - Tonsillitis/Pharyngitis (Mycoplasma pneumoniae, Chlamydia pneumoniae)
Azithromycin (Zithromax^®) Pregnancy: B; Lactation: Unk Tabs: 250 mg and Z-Pak Oral Susp: 100 mg/5 mL, 200 mg/5 mL	Children ≥6 months: 10 mg/kg/day (max 500 mg) PO daily × 1 day, then 5 mg/kg/day (max 250 mg) PO daily × 4 days. 100 mg/5 mL 10 kg (22 lb) = 1 tsp (5 mL) × 1 day, then ½ tsp (2.5 mL) daily for days 2-5. 200 mg/5 mL 20 kg (44 lb) = 1 tsp (5 mL) × 1 day, then ½ tsp (2.5 mL) daily for days 2-5.	Food: Oral suspension should be taken 1 hour before or 2 hours after food. Tablets may be taken without regard to food. Important side effects: Nausea, diarrhea, elevated LFTs.
	30 kg (66 lb) = 1.5 tsp × 1 day, then ¾ tsp daily for days 2-5. Adult: Dispense one Z-Pak.
Clarithromycin (Biaxin, Biaxin XL^®) Pregnancy: C; Lactation: Unk Tabs: 250 mg, 500 mg Extend Release Tab (XL): 500 mg Oral Susp: 125 mg/5 mL, 250 mg/5 mL	Children ≥6 months: 15 mg/kg/day (max 1 g/day) in divided doses twice daily for 7-14 days. 125 mg/5 mL @ 15 mL/kg/day 9 kg (20 lb) = ½ tsp (2.5 mL) Q12H 17 kg (37 lb) = 1 tsp (5 mL) Q12H 250 mg/5 mL @ 15 mL/kg/day 17 kg (37 lb) = ½ tsp (2.5 mL) Q12H 25 kg (55 lb) = ¾ tsp Q12H 33 kg (73 lb) = 1 tsp (5 mL) Q12H Adult: 500 mg PO twice daily or 1 gXL PO once daily for 7-14 days.	Food: Extended release tablet with food. Others without regard to food. Important side effects: Nausea, drug interactions.
Doxycycline (Vibramycin^®) Generics available Pregnancy: D; Lactation: Unsafe Caps: 50 mg, 100 mg Tabs: 50 mg, 100 mg	Adolescents ≥8 years or Adult: 100 mg PO twice daily for 7-14 days.	Food: May take with food if GI upset occurs. Take 1 hour before or 2 hours after antacids, iron, milk, or other dairy products. Take with full glass of water to prevent esophagitis.
Erythromycin estolate or base (Ilosone^®, E-mycin^®, Ery-Tab^®) Generics available Pregnancy: B; Lactation: Unsafe Estolate: Tabs: 500 mg Caps: 250 mg Oral Susp: 250 mg/5 mL, 400 mg/5 mL Base: Tabs: 250 mg, 333 mg, 500 mg Caps: 250 mg	Children: 20-40 mg/kg/day estolate (max 2 g/day) in two to four divided doses daily for 7-14 days. 125 mg/5 mL @ 20 mg/kg/day 4-6 kg (10-15 lb) = ½ tsp (2.5 mL) Q12H 7-11 kg (16-25 lb) = 1 tsp (5 mL) Q12H 12-16 kg (26-35 lb) = 1½ tsp (7.5 mL) Q12H 250 mg/5 mL @ 20 mg/kg/day 17-25 kg = 1 tsp (5 mL) Q12H 26-37 kg = 1½ tsp (7.5 mL) Q12H >38 kg = 500 mg Q12H Adult: Erythromycin Base or Estolate 500 mg PO four times daily for 7-14 days.	Important side effects: Photosensitivity (use sunscreen), esophagitis. May discolor fingernails.
		Food: May take with or without meals. Take with food if causes GI upset. Important side effects: GI upset, hepatitis.