Drug

 

 

Typical Dosing

 

 

 

Penicillin V Potassium

Pen-Vee K® Veetids®

Generics available

Pregnancy: B; Lactation: Unk

Tabs: 250 mg, 500 mg

Powder for Oral Suspension:

125 mg/5 mL

250 mg/5 mL

 

Children <12 years: 25-50 mg/kg/day in divided doses every 6 to 8 hours (max 3 g/day)

 

125 mg/5 mL @ 25 mg/kg/day

10 kg (22 lb) = 1/2 tsp (2.5 mL) Q6H

15 kg (33 lb) = 3/4 tsp Q6H

20 kg (44 lb) = 1 tsp (5 mL) Q6H

>20 kg (44 lb) = Use adult dose.

 

250 mg/5 mL @ 50 mg/kg/day

10 kg (22 lb) = 1/2 tsp (2.5 mL) Q6H

15 kg (33 lb) = 3/4 tsp Q6H

20 kg (44 lb) = 1 tsp (5 mL) Q6H

>20 kg (44 lb) = Use adult dose.

 

Children ≥12 years to Adult: 125-500 mg PO every 6 to 8 hours.

Food: Take 1 hour before or 2 hours after meals. May take with food if GI upset occurs.

 

Important side effects: Bad taste, GI upset, vomiting, diarrhea, agitation, seizures, rash, bleeding abnormalities, decreased WBC count, drug fever, superinfection.

 

Caution: Avoid use in patients with history of severe penicillin allergy. Use with caution in patients with history of seizures.

 

Do not need to adjust dose in renal disease.