GENITOURINARY - Prostatitis, Acute Bacterial (E. coli, Enterobacteriaceae, N. gonorrhoeae, C. trachomatis, Enterococci [less commonly})
Ciprofloxacin (Cipro^®) Tabs: 250 mg, 500 mg, 750 mg		Adult: 500 mg PO twice daily for 4 weeks.		Food: Take on empty stomach 1 hour before or 2 hours after a meal. May take with food if it causes GI upset, but avoid large amounts of dairy products.
				May take 2 hours before or 6 hours after sucralfate, antacids, aluminum, magnesium, calcium, zinc, iron, sucralfate, vitamins, or mineral supplements. Important side effects: Photosensitivity, dizziness. Reduce dose in renal disease (CrCl <50 mL/min).
Levofloxacin		Adult: 500 mg PO daily for 4 weeks.		Food: May take with or without meals.
(Levaquin^®) Tabs: 250 mg, 500 mg				Do not take within 2 hours of antacids, magnesium, calcium supplements, zinc, aluminum, sucralfate, vitamins, or minerals (iron or zinc).
				Important side effects: Photosensitivity, dizziness.
				Reduce dose in renal disease (CrCl <50 mL/min).
Ofloxacin (Floxin^®) Tabs: 200 mg, 300 mg, 400 mg		Adult: 400 mg PO twice daily for 4 weeks.	Food: Take on empty stomach. Do not take within 2 hours of antacids, magnesium, calcium, zinc, iron, aluminum, sucralfate, vitamins, or mineral supplements. Important side effects: Nausea, photosensitivity, dizziness. Reduce dose in renal disease (CrCl <50 mL/min).
Trimethoprim/ sulfamethoxazole (Bactrim^®, Septra^®) Generics available Single Strength (SS) Tabs: 80 mg/400 mg Double Strength (DS) Tabs: 160 mg/800 mg		Adult: 1 DS tablet PO twice daily for4 weeks.	Food: May take without regard to food. Encourage fluids. Important side effects: Photosensitivity, rash. Reduce dose in renal disease (CrCl <30 mL/min).
GENITOURINARY - Prostatitis, Chronic Bacterial (Enterobacteriaceae, Enterococci) Most cases of “prostatitis” are not caused by bacterial infection. Chronic prostatitis is characterized by relapsing bacteriuria.
Ciprofloxacin (Cipro^®) Tabs: 250 mg, 500 mg, 750 mg	Adult: 500 mg PO twice daily for 6-12 weeks.		Food: Take on empty stomach 1 hour before or 2 hours after a meal. May take with food if it causes GI upset, but avoid large amounts of dairy products. May take 2 hours before or 6 hours after sucralfate, antacids, aluminum, magnesium, calcium, zinc, iron, sucralfate, vitamins, or mineral supplements.
			Important side effects: Photosensitivity, dizziness.
			Reduce dose in renal disease (CrCl <50 mL/min).
Levofloxacin (Levaquin^®) Tabs: 250 mg, 500 mg	≥18 and Adult: 500 mg PO daily for 6-12 weeks.		Food: May take with or without meals. Do not take within 2 hours of antacids, magnesium, calcium supplements, zinc, aluminum, sucralfate, vitamins, or minerals (iron or zinc).
			Important side effects: Photosensitivity, dizziness.
			Reduce dose in renal disease (CrCl <50 mL/min).
Ofloxacin (Floxin^®) Tabs: 200 mg, 300 mg, 400 mg	Adult: 400 mg PO twice daily for 6-12 weeks.		Food: Take on empty stomach. Do not take within 2 hours of antacids, magnesium, calcium, zinc, iron, aluminum, sucralfate, vitamins, or mineral supplements.
			Important side effects: Nausea, photosensitivity, dizziness.
			Reduce dose in renal disease (CrCl <50 mL/min).
Doxycycline (Vibramycin^®) Generics available Caps: 50 mg, 100 mg   Tabs: 100 mg	Adult: 100 mg PO twice daily for 6-12 weeks.		Food: May take with food if GI upset occurs. Take 1 hour before or 2 hours after antacids, iron, milk, or other dairy products. Take with full glass of water to prevent esophagitis.
			Important side effects: Photosensitivity, use sunscreen. Esophagitis. May discolor fingernails.
Trimethoprim/Sulfamethoxazole (Bactrim^®, Septra^®) Generics available Single Strength (SS) Tabs: 80 mg/400 mg Double Strength (DS) Tabs: 160 mg/800 mg	Adult: 1 DS tablet PO twice daily for 6-12 weeks.		Food: May take without regard to food. Encourage fluids. Important side effects: Photosensitivity, rash. Reduce dose in renal disease (CrCl <30 mL/min).