GENITOURINARY - STD, Chlamydia (Chlamydia trachomatis) General statement: Instruct patient to refer sex partner for evaluation and treatment. Patient and partner should abstain from intercourse until after completion of course of therapy (7 days after single-dose therapy).
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Azithromycin (Zithromax®) Pregnancy: B; Lactation: Unk
Tabs: 250 mg Powder for Oral Suspension: 1 g |
Child ≥45 kg and Adult: 1 g PO ´ 1 dose. |
Food: 1-g powder packet for oral suspension and tablets may be taken without regard to food.
Important side effects: Nausea, diarrhea, elevated LFTs.
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Doxycycline (Vibramycin®) Generics available Pregnancy: D; Lactation: Unsafe
Caps: 50 mg, 100 mg Tabs: 100 mg |
Child ≥8 years and Adult: 100 mg PO twice daily ´ 7 days. |
Food: May take with food if GI upset occurs. Take 1 hour before or 2 hours after antacids, iron, milk, or other dairy products. Take with full glass of water to prevent esophagitis.
Important side effects: Photosensitivity, use sunscreen. Esophagitis. May discolor fingernails. |
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Erythromycin Base Alternative (E-Mycin®, Ery-Tab®) Generics available Pregnancy: B; Lactation: Safe
Tabs: 250 mg, 333 mg, 500 mg Caps: 250 mg
*May be less effective than recommended alternatives. Reserve for Children <45 kg or others intolerant to recommended drugs.
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Children <45 kg: 50 mg/kg/day (NTE 2000 mg/day) in divided doses four times daily for 10-14 days.
Adolescents and Adult: 500 mg four times daily for 7 days. |
Food: May take with or without meals.Take with food if causes GI upset.
Important side effects: GI upset, hepatitis, drug interactions. |
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Ofloxacin (Floxin®) Pregnancy: C; Lactation:Unk Tabs: 200 mg, 300 mg, 400 mg - |
Adult: 300 mg PO twice daily for 7 days. |
Food: Take on empty stomach. Do not take within 2 hours of antacids, magnesium, calcium, zinc, iron, aluminum, sucralfate, vitamins, or mineral supplements.
Important side effects: Nausea, photosensitivity, dizziness.
Reduce dose in renal disease (CrCl <50 mL/min).
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GENITOURINARY - STD, Chlamydia, Pregnancy (Chlamydia trachomatis)
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Azithromycin (Zithromax®) Pregnancy: B; Lactation: Unk
Tabs: 250 mg Powder for Oral Suspension: 1 g
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Adolescents and Adult: 1 g PO ´ 1 dose. |
Food: 1 g powder packet for oral suspension and tablets may be taken without regard to food.
Important side effects: Nausea, diarrhea, elevated LFTs.
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Erythromycin Base (E-Mycin®) Generics available Pregnancy: B; Lactation: Safe
Tabs: 250 mg, 500 mg Caps: 250 mg |
Adolescent and Adult: 500 mg four times daily ´ 7 days (recommended)
or, if gastrointestinal intolerance,
250 mg four times daily 14 ´ days.
Not as effective as azithromycin. Consider retesting in 2-3 weeks. |
Food: May take with or without meals. Take with food if causes GI upset.
Important side effects: GI upset, hepatitis, drug interactions.
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