GENITOURINARY - STI, Trichomoniasis (Trichomonas vaginalis)

General statement: Effective alternatives to metronidazole are not available in the United States.Consider desensitizing persons with metronidazole allergy. Sex partners should be treated.Patient and partner should avoid sex until therapy is completed and they are symptomatic.

 

 

Metronidazole

(Flagyl®)

Generics available

Pregnancy: B; Lactation: Unsafe

 

Tabs: 250 mg, 500 mg

 

Adolescents and Adult: 2 g ´ 1 dose or 500 mg twice daily for 7 days.

 

Food: Administer on empty stomach unless GI upset occurs, then with food.

 

Important side effects: Dizziness, headache, confusion, seizures, nausea, metallic taste, insomnia, paresthesias. May cause Disulfiram-like reaction - avoid alcohol.

 

 

GENITOURINARY - STI, Trichomoniasis - Pregnancy (Trichomonas vaginalis)

 

Metronidazole

(Flagyl®)

Generics available

Pregnancy: B; Lactation: Unsafe

 

Tabs: 250 mg, 500 mg

 

*Consider deferring treatment until after first trimester.

 

 

Adolescents and Adult: 2 g PO ´ 1 dose.

 

Food: Administer on empty stomach unless GI upset occurs, then with food.

 

Important side effects: Dizziness, headache, confusion, seizures, nausea, metallic taste, insomnia, paresthesias. Avoid alcohol.