GENITOURINARY - UTI - Pregnant Woman, Asymptomatic Bacteriuria or Uncomplicated Cystitis

 

 

Amoxicillin

(Amoxil®)

Generics available

Pregnancy: B; Lactation: Unsafe

 

Caps: 250 mg, 500 mg

Tabs: 500 mg, 875 mg  

E. coli resistance increasing.

 

 

 

Adolescent and Adult:

500 mg every 8 hours for 7 days.

 

Food: With or without meals.

 

Important side effects: Diarrhea and nausea. May cause nonallergic maculopapular rash.

 

Reduce dose in renal disease

(CrCl <30 mL/min).

 

Cephalexin

(Keflex®)

Generics available

Pregnancy: B; Lactation: Unk

 

Tabs: 250 mg, 500 mg, 1 g    

Caps: 250 mg, 500 mg  

 

Adolescent and Adult:

500 mg every 6 hours for 7 days.

 

Food: May take with food if GI upset occurs.

 

Important side effects: GI upset, diarrhea.

 

Reduce dose in renal disease

(CrCl <40 mL/min).

 

 

Trimethoprim/

sulfamethoxazole*

(Bactrim®, Septra®)

Generics available

Pregnancy: C; Lactation: Unsafe

 

Single strength (SS) Tabs:

80 mg/400 mg

 

Double Strength (DS) Tabs:

160 mg/800 mg

 

*E. coli resistance may be 15-20% and increasing.

* Avoid using near term (within 2 weeks of delivery).

 

 

Adolescent and Adult:

1 DS tablet twice daily for 7 days.

 

Food: May take without regard to food.

Encourage fluids.

 

Important side effects: Photosensitivity, rash

.

Reduce dose in renal disease

(CrCl <30 mL/min).